A shadow economy for unlicensed weight-loss drugs is being driven by TikTok fitness influencers and vendors on messaging platforms, based on new investigations.
The experimental drug, which is still in research studies, is being promoted by social media influencers for its supposed fat-burning properties. Viewers are urged to message these accounts directly for supplier links, while also receiving promotional offers.
Additionally, a robust market exists on Telegram, where communities with thousands of members share “before and after” photos, injection guides and assertions of next-day British shipping. Vendors promote the drug there before redirecting buyers to other platforms for transactions.
Retatrutide is an experimental injection developed by American pharmaceutical company Eli Lilly. The drug affects three gut hormones – GLP-1, GIP and pancreatic hormone. Preliminary studies suggest it could help individuals lose up to 25% of their total weight. Nicknamed the “triple G”, the substance is being hailed digitally as the successor to Ozempic.
Nevertheless, physicians and pharmacists have cautions that the sale of what is still an unapproved drug in the UK is a cause for concern and could result in individuals injecting products of unknown origin.
Several professionals stated the demand for the experimental drug could be connected to the rising price of approved weight loss treatments such as Mounjaro.
Selling the unapproved drug on social media or messaging apps is illegal in the UK, as it is an unlicensed medication that must not be promoted or distributed for human use under the Human Medicines Regulations 2012.
Several content creators attempt to sidestep the regulations by referring to the substance as a “research chemical” or citing it as “not for human consumption”. The substance is not a controlled substance, but promotion and supply can still violate pharmaceutical, advertising, and consumer regulations, potentially leading to fines, prosecution or imprisonment.
According to TikTok, the platform has removed violative content and banned associated hashtags and search suggestions. The company said it was committed to keeping the platform secure and investing in strengthening compliance measures.
Investigations also discovered groups with up to 9,000 members selling the experimental drug using the platform's integrated search feature, which operates like a public directory. Typing “retatrutide” immediately displays channels with numerous of users, populated with photos of slimming results, glowing testimonials and step-by-step guides for preparing or administering at home.
Within moments of entering one group, a seller shared contact information, where the majority of purchases take place. The seller sent an instruction manual and promised shipping within 48 hours. When asked whether the substance was authentic, one vendor said: “You can’t be sure.” Another shared a photo of a supposed testing documentation. Not one inquired about weight, medical conditions or past usage.
Inside these groups, messages display black plastic parcels with Royal Mail labels, claiming to include fresh supplies. One communication stated: “It took eight of us to load them this morning.”
Customers can choose between powder vials, prepared at home with sterile water, or ready-to-use pens typically sold at £160 for 20mg. When questioned how much time a pen should last, vendors give conflicting responses ranging from a several days to “depends on your body”.
A spokesperson for the messaging service said it regularly monitored harmful material on its platform including content that promoted the “misuse of controlled medications”. The organization added that it eliminated “millions of pieces of harmful content each day”.
“People are injecting substances they can’t verify. Even if the research behind this drug is valid, these online products may not contain what they claim,” stated a pharmacy expert, the director of pharmaceutical services at Chemist4U.
A medical professional of Asda Online Doctor connected the increase in demand to current cost increases for approved slimming medications such as Mounjaro. “With costs increasing, individuals are turning to online platforms. But fake injections are highly dangerous. You cannot know what’s contained or whether the conditions they were made in was clean,” she said.
Her team has already encountered individuals harmed by personal administration from unverified suppliers. “We recognize the frustration, but purchasing from Telegram or communication platforms is gambling with your health,” said the doctor. “These substances could be impure or incorrectly dosed.”
A representative from the pharmaceutical company stated retatrutide was in phase 3 research studies and had not been reviewed or approved by any regulatory agency anywhere in the world. “Consequently at this time no one can sell [it] for human use,” they explained, noting that any item “misleadingly claiming itself as a Lilly investigational substance not yet approved … may expose users to potentially serious health risks”.